Senior Director/VP, New Product Planning & Competitive Intelligence
Sionna Therapeutics is a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for CF by developing novel medicines that normalize the function of the CFTR protein. Sionna’s goal is to deliver differentiated medicines for people living with CF that can restore their CFTR function to as close to normal as possible by directly stabilizing CFTR’s nucleotide-binding domain 1 (NBD1), which the company believes is central to potentially unlocking meaningful improvements in clinical outcomes and quality of life for people with CF. Leveraging over a decade of the co-founders’ extensive research on NBD1, the company is advancing a pipeline of novel small molecules engineered to correct the defects caused by the F508del genetic mutation, which resides in NBD1. Sionna is also developing a portfolio of complementary CFTR modulators that are designed to work synergistically with its NBD1 stabilizers to improve CFTR function.
Position Summary
The Senior Director, New Product Planning & Competitive Intelligence will lead Sionna’s commercial planning for its pipeline portfolio including assessing unmet need, opportunities for differentiation, refining the target product profile, revenue forecasting, Market Access and HEOR planning as well as evaluating the competitive landscape. This role will be a member of the program team as the commercial lead and will report to the Chief Financial Officer.
We are accepting resumes for the position at careers@sionnatx.com.
Key Responsibilities:
- Lead development of commercial strategy for Sionna’s pipeline by collaborating with internal cross-functional teams to determine Target Product Profiles (TPPs) and future product positioning.
- Conduct market assessments, competitive landscape analyses, product positioning, market access and pricing strategy, and initial health economics and outcomes research strategy.
- Contribute to overall portfolio strategy and prioritization.
- Generate program assumptions, market sizing, and revenue forecasts for pipeline programs and provide strategic input on asset development and portfolio prioritization decisions.
- Evaluate in-licensing and partnering opportunities from a commercial perspective.
- Lead commercial due diligence efforts for potential acquisitions or partnerships.
- Design and oversee primary and secondary market research initiatives.
- Analyze market dynamics, patient journeys, treatment paradigms, and payer landscapes.
- Engage with key opinion leaders, advisory boards, payers, and patient advocacy groups to gather insights.
- Participate on program team as the commercial lead and work closely with Clinical Development, Medical Affairs, Regulatory Affairs, and other cross-functional teams to align commercial strategy with clinical, scientific, and regulatory approaches.
- Identify key clinical evidence necessary to maximize asset value working collaboratively with Clinical Development.
- Prepare and deliver high-quality presentations to senior leadership.
- Provide strategic recommendations to inform corporate decision-making on asset development and portfolio prioritization.
- Articulate the commercial vision and value proposition of Sionna’s innovative Cystic Fibrosis portfolio.
Experience, Education, and Qualifications:
- 9+ years of experience in pharmaceutical/biotech industry and/or management consulting, with a strong background in new product planning and commercial strategy (rare disease and/or pulmonary experience preferred).
- Experience as a member of the sales, marketing or market access & reimbursement organization or have led the launch and management of a new drug or new indication of an existing drug.
- Deep understanding of drug development process, clinical trial design, and regulatory pathways.
- Proven track record in developing commercial strategies for clinical-stage assets.
- Strong analytical skills with the ability to synthesize complex data into actionable insights.
- Excellent communication and presentation skills, with the ability to influence senior leadership.
- Bachelor’s degree in related field required; Advanced degree (MBA, PharmD, or PhD in life sciences) preferred.
