Marcella Kuhlman Ruddy, M.D.

Dr. Ruddy serves as a board member of Sionna and is the Chief Medical Officer of Tectonic Therapeutic, Inc., a biotechnology company focused on therapeutic proteins and antibodies that modulate G-protein coupled receptors. She also serves on the board of directors of Upstream Bio, Inc. Dr. Ruddy has over 20 years of experience in drug development, including a leadership role as Vice President of Clinical Development, Immunology at Regeneron Pharmaceuticals, Inc. She is a trained pulmonologist who founded and led the Adult Cystic Fibrosis center at Massachusetts General Hospital in Boston, Massachusetts. Dr. Ruddy began her drug development career at Merck & Co Inc. and has also served on the board of directors of Polarean, Inc. Dr. Ruddy received a B.A. in history from Princeton University and an M.D. and an M.S. from Washington University, School of Medicine, St. Louis.